PARTE UTILIZADA= Used part: Hoja y fruto.

ACCIÓN FARMACOLÓGICA= Pharmacological action: Sudorífico y antidiarreico.

COMPOSICIÓN QUÍMICA= Chemical composition: Las hojas contienen un aceite esencial 0,48% (p, cimol, alfa- y beta-pineno, limoneno). También se han aislado algunas biflavonas como amentoflavona, 2,3-dihidroamentoflavona, 7-O-metilamento-flavona, isoquercitina y 4```-monoamentoflavona. Del duramen se han aislado 4-isopropiltropolona, podofilotoxina y otro lignano: deoxipodofilotoxina. De las hojas, diterpeno 2, burseran lactona y pisiferol.

ZONA GEOGRÁFICA= Geografical zone: Chile.

DIVERSIDAD GENÉTICA Y MEJORAMIENTO DE PLANTAS MEDICINALES= Medicinal plants and improvement of medicinal herbs:

An enriched genomic library was constructed and 9 novel polymorphic tetranucleotide microsatellite markers developed for Austrocedrus chilensis, the most economically important native conifer in the Andean Patagonian region.  Polymorphism was investigated for these markers in 48 individuals from two populations.  Nos. of alleles ranged from 3 to 19 and levels of obsd. heterozygosity among the 9 loci ranged from 0.32 to 0.95.  No locus combinations exhibited linkage disequil.  These polymorphic markers will be useful tools for the study of demog. and gene flow and more in general for population and conservation genetics of this species.  

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) Knowledge about current patterns of genetic structure of populations together with the evolutionary history of a species helps to understand and predict the adaptation of populations to future climate change.  We assayed variation at nuclear microsatellite markers among peripheral vs. continuous populations of the temperate South American species Austrocedrus chilensis, to investigate the role of historical vs. demog. forces in shaping population genetic structure.  This species occurs in continuous populations in the west and central distribution range, but becomes highly fragmented at the eastern limit, which comprised ice-free areas during Quaternary glaciations and has extreme climatic conditions at present times.  Bayesian anal. methods identified two contrasting patterns of genetic structure; (I) populations from humid, mesic and peri-glacial regions formed a single deme with relatively low genetic differentiation and high admixt. levels whereas (II) a highly heterogeneous genetic structure with low level of admixt. was found in the steppe, towards the east and northeast limit of the distribution range.  In the steppe, population fragmentation, restricted gene flow and isolation-by-distance were also inferred.  In addn., several small steppe populations showed high genetic diversity and divergent gene pools, suggesting that they constitute ancient refuges from pre-Holocene glaciations with just a subgroup of them contributing significantly to post-glacial spread.  These results are discussed in relation to patterns of genetic variation found for other temperate species and the contribution of the particular southern Andes topog. and climate to post-glacial spread.

1) 270 (doscientos setenta) plantas medicinales iberoamericanas. Santiago de Bogotá : CYTED-SECAB, 1995, pp.255-256.

2) Arana, Maria Veronica; Buonamici, Anna; Sebastiani, Federico; Alia, Ricardo; Gallo, Leonardo A.; Marchelli, Paula; Moreno, Carolina; Vendramin, Giovanni G.  Development of highly polymorphic tetranucleotide microsatellite markers in  Austrocedrus   chilensis.  Molecular Ecology Resources. 2008 vol.8, nº4, 887-889. 2008.

3) Arana, Maria Veronica; Gallo, Leonardo A.; Vendramin, Giovanni G.; Pastorino, Mario J.; Sebastiani, Federico; Marchelli, Paula.    High genetic variation in marginal fragmented populations at extreme climatic conditions of the Patagonian Cypress Austrocedrus chilensis.     Molecular Phylogenetics and Evolution. 2010 vol.54, nº3,  941-949.