PARTE UTILIZADA= Used part: Leño.

ACCION FARMACOLOGICA= Pharmacological action: Antiinflamatorio.

ZONA GEOGRAFICA= Geografical zone: Brasil y NE de Argentina. 

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) An acidic polysaccharides fraction (APS) obtained from Cedrela tubiflora leaves was tested for antiviral activity.  This fraction inhibited the replication of HSV-2 and VSV, while the replication of poliovirus was not affected.  APS was not virucidal, but no cytotoxicity was present in the different concns. of APS assayed.

2) Human peripheral blood monocytes and polymorphonuclear leukocytes treated with leaf aqueous extracts of the Meliaceae tree Cedrela tubiflora showed a diminution in both their phagocytic and respiratory burst activities.  Besides, the extract inhibited the proliferation of Concanavalin A stimulated lymphocytes.  A decrease in the hemolytic capacity of the human complement was also observed.  The significance of the inhibitory effect observed over some components of the human immune system closely related with the inflammatory process is discussed.

1) TOURSARKISSIAN, Martín. Plantas medicinales de Argentina : sus nombres botánicos, vulgares, usos y distribución geográfica. Buenos Aires : Hemisferio Sur, 1980. p.86.

2) CRAIG, M. I.; BENENCIA, F.; COULOMBIA, F. C. Antiviral activity of an acidic polysaccharides fraction extracted from Cedrela tubiflora leaves.  Fitoterapia. 2001, vol.72, nº2, p.113-119.
 
3) BENENCIA, F., et al. Immunomodulatory activities of Cedrela tubiflora leaf aqueous extracts. Journal of ethnopharmacology. 1995, vol.49, nº3, p.133-129.