PARTE UTILIZADA= Used part: Partes aéreas.
ACCIÓN FARMACOLÓGICA= Pharmacological action: Hepático, diurético, emenagogo.
COMPOSICIÓN QUÍMICA= Chemical composition: Acaena splendens H. et A. has been used in Chilean folk medicine for the treatment of fever and inflammation. A description of the in vivo reduction of bacterial pyrogen-induced fever in rabbits and carrageenan-induced paw oedema in guinea pigs is presented. The methanol extract named ME-1, obtained after succesive extractions with petroleum ether and dichloromethane, showed a strong antipyretic action (45.7% of effect), though the antiinflammatory activity was only observed after submitting this extract to column fractionation, giving a crude mixture of flavonoids named C4 with both activities (55.7% and 98.9% of antiinflammatory and antipyretic effect respectively at a dose of 600 mg/kg). The bioassay-guided fractionation by column chromatography afforded the active fraction, which contained (-,-)-epicatechin, tiliroside, 7-O-acetyl-3-O-B-D-glucosyl-kaempferol and 7-B-D-glucosyloxy-5-hydroxy-chromone. Copyright © 2002 John Wiley & Sons, Ltd.
ZONA GEOGRAFICA= Geografical zone: Chile y Argentina.
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Hojas
Usos tradicionales: padecimientos hepáticos; limpieza renal y de las vías urinarias. La infusión se prepara con 2 cucharadas de hojas secas y trituradas para 1 litro de agua recién hervida, dejar reposar durante 10 minutos: beber 1 taza 3 veces al día.
Efecto: diurético, depurativo, anti-inflamatorio.
1) TOURSARKISSIAN, Martín. Plantas medicinales de Argentina : sus nombres botánicos, vulgares, usos y distribución geográfica. Buenos Aires : Hemisferio Sur, 1980, p.110.
2) BACKHOUSE, N., et al. Bioactive phenolic derivatives from Acaena splendens methanol extract. Phytotherapy Research. 2002, vol.16, nº6, p.562-566.
3) Hierbas medicinales/ Chile. Ministerio de Agricultura. p.64