PARTE UTILIZADA=Used part: Partes aéreas.

ACCIÓN FARMACOLÓGICA=Pharmacological action: Purgante drástico, depurativo, diurético.

COMPOSICIÓN QUÍMICA=Chemical composition: Hypa A, a novel macrocyclic polypeptide containing 30 amino acid residues, has been isolated from the n-butanol extract of the Argentine plant Hybanthus parviflorus. The sequence, cyclo-(SCVYIPCTITALLGCSCKNKVCYNGIPCAE), was determined by automated Edman degradation, quantitative amino acid analysis and nanospray MS/MS2. Three intramolecular disulfide bridges stabilize the cyclic peptide backbone of hypa A. Using these structural features to classify the peptide as a cyclotide, we extended the distribution of that substance class to a new genus, and now propose a uniform nomenclature for cyclotides. © 2001 Elsevier Science Ltd.

ZONA GEOGRÁFICA=Geografical zone: Brasil, Uruguay.

1) GONZALEZ, Matías ; LOMBARDO, Atilio ; VALLARINO, Aida. Plantas de la medicina vulgar del Uruguay. Montevideo : Talleres Gráficos, 1937, p.43.

2) BROUSSALIS, A.M., et al. First cyclotide from Hybanthus (Violaceae). Phytochemistry. 2001, vol.58, nº1, p.47-51.