DIVERSIDAD GENÉTICA Y MEJORAMIENTO DE PLANTAS MEDICINALES:= Medicinal plants and improvement of medicinal herbs

A novel cor gene was cloned from Capsella bursapastoris (designated Cbcor15b) by RACE-PCR.  The full-length cDNA of Cbcor15b was 652 bp and contained a 417 bp open reading frame (ORF) encoding a 139-amino acid hydrophilic protein.  Multiple alignments showed that Cbcor15b had high similarity with other cold-regulated genes from Arabidopsis thaliana (cor15b, cor15a), Brassica napus (bn115, bn19 and bn26) and genes encoding late embryogenesis abundant (LEA) proteins.  The predicted CbCOR15B protein was found to have a potential chloroplast signal sequence cleavage site, two cAMP- and cGMP-dependent protein kinase (PKA and PKG) phosphorylation sites.  Cold acclimation assay showed that Cbcor15b was relevant to cold acclimation.  Our study implies that Cbcor15b might have similar functions possessed by other cor genes in increasing plants' freezing tolerance.  

PARTE UTILIZADA= Used part : Partes aéreas frescas.

ACCIÓN FARMACOLÓGICA= Pharmacological action: Se usa para combatir los catarros, en las hemorragias, hematurias y en la amenorrea.

COMPOSICIÓN QUÍMICA= Chemical composition: Alcaloides: burseína, yohimbina, ergocristina. Aminas: Aminoalcoholes como la colina (0,2-1%) y su éster: acetilcolina(0,42%); aminofenoles como la tiramina, bistamina, colina, prolina, etc. Flavonoides: diosnina, rutina, hesperidina, heterósidos de luteolina y quercetina. Otros: taninos, saponósidos, trazas de aceite esencial sulfurado (0,02%), ácido cítrico, ácido fumárico, sales de potasio (gran cantidad), aceite esencial (0,1-0,5%), glucosinolatos (sinigrina), isotiocianatos (semilla), vitamina C, vitamina K, etc.

ZONA GEOGRÁFICA= Geografical zone: Todo el mundo.

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Efectos: hemostático1, astringente2, antidiarreico3, emenagogo4.

Precauciones: no hacer tratamientos largos y no usar durante el embarazo.

Origin:
Throughout India as a weed in cultivated areas and waste places, particularly in the temperate regions up to an altitude of 4.200m.

Action:
The herb or its juice extracts are employed to check menorrhagia and haemorrhages from renal and genitourinary tract. Also used in diarrhoea and dysentery and as a diuretic.

1) GONZALEZ, Matías ; LOMBARDO, Atilio ; VALLARINO, Aida. Plantas de la medicina vulgar del Uruguay. Montevideo : Talleres Gráficos, 1937, p.89.  

2) ALONSO, Jorge R. Tratado de fitomedicina : bases clínicas y farmacológicas. Buenos Aires : ISIS, 1998, pp.314-316.

3) LIU, Sixiu, et al. Molecular cloning and characterization of a novel cold-regulated gene from  Capsella   bursa - pastoris. DNA Sequence. 2004, vol.15, nº4, p.262-268.

4) ALONSO, Jorge R. Tratado de fitomedicina : bases clínicas y farmacológicas. Buenos Aires : ISIS, 1998, p. 314.

5) Khare, C.P./ Indian Medicinal Plants. -- Nueva Dheli: Springer, 2007 . - p. 836.