PARTE UTILIZADA= Used part: Rizoma. 

ACCIÓN FARMACOLÓGICA= Pharmacological action: Cicatrizante. 

COMPOSICIÓN QUÍMICA= Chemical composition: A new sterol glycoside was isolated from the methanolic extract of roots of Senecio bonariensis. Its structure was established as sitosterol 3-O-beta;-d-glucuronopyranoside by spectral data and chemical conversions. 

ZONA GEOGRÁFICA= Geografical zone: S. de Brasil, Uruguay, E. de Argentina. 

DIVERSIDAD GENÉTICA Y MEJORAMIENTO DE PLANTAS MEDICINALES= Medicinal plants and improvement of medicinal herbs

Pyrrolizidine alkaloids (PAs) were characterized by GC-MS in inflorescences of 14 Senecio species (S. brasiliensis, S. conyzifolius, S. heterotrichius, S. oleosus, S. oxyphyllus, S. riograndensis, S. selloi, S. bonariensis, S. grossidens, S. icoglossus, S. juergensii, S. pulcher, S. ceratophylloides and S. crassiflorus) from southern Brazil, belonging to three taxonomic sections of the genus. The 1,2-saturated macrocycle diesters (such as platyphylline or rosmarinine), 1,2-saturated or unsaturated triangularine-like alkaloids such as senecioylplatinecine and senecioylretronecine were characteristic for the section Hualtatini. The section Corymbosi has, as characteristic PAs, 1,2-unsaturated 12-membered macrocyclic diesters (such as senecionine), while the section Suffrutecius is ambiguous in relation to the PA profile. The data indicate that the PA patterns are mostly in good agreement with morphological data for the sections Corymbosi and Hualtatini and that they can be useful chemotaxonomic markers at the infrageneric level. © 2003 Elsevier Science Ltd. All rights reserved. 

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) From the leaves of Senecio bonariensis Hook. & Arn. three sesquiterpenoids were isolated beta-caryophyllene (1), beta-caryophyllene oxide (2) and germacrene D (3) were characterized by GC-EI-MS, IR, 1H and 13C-NMR data.  Their ecol. and chemotaxonomical significance for the genus Senecio are discussed, as well as the biosynthetic correlation between the isolated substances.  The antimicrobial activity of substances 1 and 2 were evaluated by the microdilution method against bacterial and fungal strains.  Both compds. did not inhibit the microorganism growth at the tested concns.

2) Four toxic 10alphaH-9-oxofuranoeremophilanes were isolated and identified from the petroleum ether ext. of Senecio bonariensis.  Their 13C NMR spectral data, J1,10Altona calcn. and a correlation for 1H NMR (C6D6/CDCl3) are discussed.

1) TOURSARKISSIAN, Martín. Plantas medicinales de Argentina : sus nombres botánicos, vulgares, usos y distribución geográfica. Buenos Aires : Hemisferio Sur, 1980, p.38.

2) JARES, E.A.; TETTAMANZI, M.C.; POMILIO, A.B. Sitosterol 3-O-β-d-glucuronopyranoside from Senecio bonariensis. Phytochemistry . 1990, vol.29, nº1, p.340-341.
 
3) TRIGO, J.R., et al. Chemotaxonomic value of pyrrolizidine alkaloids in southern Brazil Senecio (Senecioneae: Asteraceae). Biochemical Systematics and Ecology . 2003, vol.31, nº9, p.1011-1022.
 
4) DE MEDEIROS DA SILVA, Chana, et al. Sesquiterpenoids of Senecio bonariensis Hook. & Arn., Asteraceae. Revista Brasileira de Farmacognosia . 2010, vol.20, nº1, p.87-92.
 
5) POMILIO, A. B.; JARES, E. A. Toxic furanoeremophilanes from Senecio bonariensis. International Journal of Pharmacognosy . 1997, vol.35, nº3, p.207-211.