PARTE UTILIZADA= Used part: Hojas. 

ACCIÓN FARMACOLÓGICA= Pharmacological action: Depurativo, diaforético, béquico. 

COMPOSICIÓN QUÍMICA= Chemical composition: From aerial parts of G. luteo-album, gnaphaliin, jaceosidin, apigenin, luteolin, apigenin and luteolin 7-glucosides, and luteolin 4'-glucoside were isolated and identified by UV and IR spectra and comparison with authentic samples. Jaceosidin was isolated from this plant for the 1st time. 

ZONA GEOGRÁFICA= Geografical zone: Argentina. 

DIVERSIDAD GENÉTICA Y MEJORAMIENTO DE PLANTAS MEDICINALES= Medicinal plants and improvement of medicinal herbs

Gnaphalium teydeum and G. luteo-album (Asteraceae) are two closely congeneric taxa native to the Canary Islands. While G. luteo-album is widespread in the Macaronesian Region, G. teydeum is endemic to the island of Tenerife and considered endangered by IUCN. Using the RAPD technique this study investigated the level and apportionment of genetic diversity of these taxa, trying to solve a taxonomic dispute related to G. teydeum. Based on the 102 DNA fragments generated by 11 primers, a high level of genetic differentiation was found between the taxa (F ST = 0.366), with G. luteo-album showing levels of genetic variability (P = 100%; H = 0.246) higher than those found in G. teydeum (P = 75.5%; H = 0.173). UPGMA dendrogram and Bayesian cluster analysis clearly separated populations from both the species. Overall, results show that although morphological differentiation between G. teydeum and G. luteo-album is not strong, they show marked molecular divergence, supporting the current taxonomic status. © 2008 Springer-Verlag. 

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) Genetic analyses of Gnaphalium's DNA showed a high degree of polymorphism in UV-B irradiated plants when compared to controls.  Among the five tested primers the four ISSR primers selected for this anal. generated a total of 189 fragments.  A high proportion of polymorphic bands ranging from 70% to 28% were found using these ISSR markers.  Nei and Li similarity indexes were used to evaluate genetic divergence among plants.  The dendrograms obtained using these markers efficiently sep. plants from different treatments.  A linear relationship was obsd. between UV-B dose and percentage of dissimilarity which may be related to DNA damage caused by the different UV-B treatments.

Origin:
Throughout India, ascending up to 3,350 m in the Himalayas.

Action:
Leaves—astringent, haemostatic, vulnerary. The tomentum is applied as counterirritant in gout, also used as tinder.

1) TOURSARKISSIAN, Martín. Plantas medicinales de Argentina : sus nombres botánicos, vulgares, usos y distribución geográfica. Buenos Aires : Hemisferio Sur, 1980.

2) MERICLI, Ali H.; ECZACILIK, Fak. Flavonoids from Gnaphalium luteo - album L. Journal of Faculty of Pharmacy of Istanbul University. 1980, vol.16, p.84-87.
 
3) GONZÁLEZ-PÉREZ, M.A., et al. Gnaphalium teydeum and Gnaphalium luteo-album: Two taxa of the Canary Islands with different genetic histories. Plant Systematics and Evolution. 2008, vol.276, nº1-2, p.39-49.
 
4) CUADRA, Pedro, et al. Effects of UV-B radiation in morpho-genetic characters of Gnaphalium luteo-album. Journal of Photochemistry and Photobiology, B: Biology. 2010, vol.101, nº1, p.70-75.

5) Khare, C.P./ Indian Medicinal Plants. -- Nueva Dheli: Springer, 2007 . - p. 836.