PARTE UTILIZADA= Used part: Hojas, partes aéreas. 

ACCIÓN FARMACOLÓGICA= Pharmacological action: Para dolencias del hígado, para mejorar la cicatrización, tónico digestivo, para estimular el funcionamiento biliar, para el dolor estomacal, afrodisíaca, para escalofríos, emenagoga.

COMPOSICIÓN QUÍMICA= Chemical composition: Se registra la presencia de heterósidos antraquinónicos (emodina, ácido crisofánico), resina, preniletina, (Schwenker, et al. 1967) flavonoides, kempferol, quercetina-3-0-metiléter. 

ZONA GEOGRÁFICA= Geografical zone: Chile. 

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) Eleven flavonoid aglycons have been isolated and identified from the external stem and leaf resin of Haplopappus baylahuen (Asteraceae).  Six of these compds. are Me derivs. of the dihydroflavonoids naringenin, eriodictyol, aromadendrin and taxifolin.  The other flavonoids are Me derivs. of kaempferol, luteolin and quercetin.  The structures were assigned on the basis of phys. and spectral data.  The biol. activity of 7-methylaromadendrin, one of the isolated compds., and of H. baylahuen infusion were evaluated by means of the model of rats intoxicated with CCl4.  The hepatoprotective effect was similar to that of the known hepatoprotector silymarin.

2) "Bailahuen" is the common name of a medicinal shrub native to Chile where this resinous herb is widely used for its liver stimulating properties.  Although the official species is Haplopappus baylahuen Remy (Asteraceae), other species of the same genus are also used in different regions as "bailahuen".  A thin layer chromatography (TLC) method for rapid identification of different species and detection of adulterations is described for four of the species: Haplopappus baylahuen, Haplopappus taeda Reiche, Haplopappus multifolius Phil., and Haplopappus remyanus Wedd.  To confirm efficiency in all species antioxidant properties were screened in resins, infusions, and methanolic extracts by tests of lipid peroxidation in erythrocytes and free radical scavenging activity by DPPH.  In both studies Haplopappus baylahuen showed the lowest antioxidant capacity.  In DPPH analyses, infusion and resins of Haplopappus baylahuen also showed the lowest and Haplopappus remyanus the major inhibiting activity of free radicals, while Haplopappus multifolius proved to have the highest result when the methanolic extracts were used.  The chemical characterization of the studied species showed important levels of flavonoids and coumarins, with flavonoids predominating in Haplopappus taeda, coumarins in Haplopappus multifolius and both of them in Haplopappus baylahuen and Haplopappus remyanus.

1) 270 (doscientos setenta) plantas medicinales iberoamericanas. Santiago de Bogotá : CYTED-SECAB, 1995.

2) NUNNEZ-ALARCON, Juana; et al. Epicuticular flavonoids from Haplopappus baylahuen and the hepatoprotective effect of the isolated 7-methylaromadendrin. Boletín de la Sociedad Chilena de Química. 1993, vol.38, nº1, p.15-22.
 
3) VOGEL, Hermine; et al. Antioxidant properties and TLC characterization of four Chilean Haplopappus-species known as bailahuen. Journal of Ethnopharmacology. 2005, vol.97, nº1, p.97-100.