PARTE UTILIZADA= Used part: Planta entera fresca.

ACCIÓN FARMACOLÓGICA= Pharmacological action: Astringente, vulneraria, detersiva y tónica.

POSOLOGÍA= Posology: Flujos del vientre. Cocer durante 10 minutos 35 gramos de la planta seca o 60 g de la planta fresca en 1 litro de agua. Filtrar y tomar de 3 a 4 tazas al día.

COMPOSICIÓN QUÍMICA= Chemical composition: Aceite esencial (acre) que lleva persicariol, flavonas, quercitina, persicarina y tanino.

ZONA GEOGRÁFICA= Geografical zone: Caminos de Santiago

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs

1) Polygonum L. genus (Polygonaceae) is represented in Argentina by 21 species and some of them have been used in the traditional medicine of our country to treat affections related with fungal infections, such as skin ailments and vaginal diseases.  With the aim of contributing to the correct ethnopharmacol. use of this genus, in the present work we describe the antifungal properties of P. persicaria (species not studied up to now) and the bio-guided isolation of the main active compds.  Results showed that dichloromethane exts. was the most active with MICs (Min. Inhibitory Concns.) between 31.2 - 1000 mg/mL, validating the ethnopharmacol. use of P. persicaria to treat affections related with fungal infections in the Argentinean traditional medicine.

Patente extraída del Chemical Abstracts= Patent extrated from the Database Chemical Abstracts
 
Methods and therapeutic compositions comprising plant extracts for the treatment of cancer.      Cyr, Benoit.  (Biopharmacopae Design International Inc., Can.).    PCT Int. Appl.  (2006),     165 pp.  CODEN: PIXXD2  WO  2006039807  A1  20060420  Designated States W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM.  Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IS, IT, LU, MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG.  Patent  written in English.    Application: WO  2005-CA1576  20051017.  Priority: US  2004-619393P  20041015; WO  2005-CA1576  20051017; CA  2002-2400936  20020830; WO  2003-CA1284  20030902; US  2005-526387  20051006; US  2008-577292  20080307.  CAN 144:381990    AN 2006:365429    CAPLUS   (Copyright (C) 2011 ACS on SciFinder (R))  

A method of treating cancer by targeting two proteases, MMP-9 and cathepsin B is provided.  Therapeutic compns. comprising one or more plant exts. that inhibit MMP-9 and/or cathepsin B, which are capable of inhibiting neoplastic and/or endothelial cell migration, tumor growth, tumor-induced angiogenesis and/or metastasis are also provided.  The therapeutic compns. of the invention can be used in the treatment of cancer, and, methods of inhibiting tumor growth, tumor metastasis, and/or tumor-induced angiogenesis using the therapeutic compns. alone or in combination with an anti-cancer agent are, therefore, also provided.

1) ALFARO, Txumari, Plantas y remedios naturales de los caminos de santiago. Barcelona: B.S.A. 2008, p. 180.
 
2) DERITA, Marcos; ZACCHINO, Susana. Validation of the ethnopharmacological use of Polygonum persicaria for its antifungal properties.  Natural Product Communications. 2011, vol.6, nº7, p.931-933.