PARTE UTILIZADA=Used part: Hojas frescas y planta florida frescas.

ACCIÓN FARMACOLÓGICA=Pharmacological action: Astringente, hemostática, depurativa, pectoral, vulneraria.

POSOLOGÍA=Posology: Inflamación de encías e inflamación de la lengua. Poner a hervir en un recipiente 60 g de la planta florida entera en 1 litro de agua durante 10 minutos. Dejar reposar durante 15 minutos y colar. Se emplea para hacer enjuagues de boca, 4 o 6 veces al día. Cada enjuague debe tener una duración de 3 ó 4 minutos.

COMPOSICIÓN QUÍMICA=Chemical composition: Saponina, un principio amargo, tanino, alantoína, esencia, azúcar y ácidos orgánicos.

ZONA GEOGRÁFICA=Geografical zone: Caminos de Santiago.

DIVERSIDAD GENÉTICA Y MEJORAMIENTO DE PLANTAS MEDICINALES= GENETIC DIVERSITY AND IMPROVEMENT OF MEDICINAL PLANTS:
 
DNA barcoding involves sequencing a std. region of DNA as a tool for species identification.  However, there has been no agreement on which region(s) should be used for barcoding land plants.  To provide a community recommendation on a std. plant barcode, the authors compared the performance of 7 leading candidate plastid DNA regions (atpF-atpH spacer, matK gene, rbcL gene, rpoB gene, rpoC1 gene, psbK-psbI spacer, and trnH-psbA spacer).  Based on assessments of recoverability, sequence quality, and levels of species discrimination, the 2-locus combination of rbcL+matK was recommended as the plant barcode.  This core 2-locus barcode will provide a universal framework for the routine use of DNA sequence data to identify specimens and contribute toward the discovery of overlooked species of land plants.  Sequence data are deposited in GenBank/EMBL/DDBJ with accession nos. GQ247894-GQ248069, GQ248071-GQ248710, GQ248715-GQ249040, GQ273984-GQ273987, GQ274310-GQ274318, and GQ335519-GQ335521.

ÚLTIMOS AVANCES EN LA QUÍMICA Y ACTIVIDADES BACTERIOLÓGICAS EN LAS PLANTAS MEDICINALES= RECENT DEVELOPMENTS IN THE CHEMICAL AND BACTERIOLOGICAL ACTIVITIES IN MEDICINAL PLANTS:

We have investigated the influence of Sanicula europaea L. exts. on influneza virus growth in MDCK cells.  Fractions I, II, and III sepd. from Sanicula ext. with Sephadex column chromatog. were found to be non-toxic against MDCK cells.  The growth of influenza A/PR/8/34 was completely inhibited by these fractions, while that of influenza B/Lee/40 was not affected.  Fractions II and III have been shown not to have a direct virucidal activity on influneza A/PR/8/34.  Influenza A/Vic/1/75 produced microscopic plaques in the presence of the ext.  In vitro RNA synthesis with virla RNA-dependent RNA polymerase was also inhibited by a water sol. ext. of Sanicula.  These observations suggest that the Sanicula ext. contains an anti-influenza virus substance.

Patente extraída del Chemical Abstracts=Extracted patent of the Database Chemical Abstracts : 

 
Antimicrobial activity of biologically stabilized silver nanoparticles.      Paknikar, Kishore Madhukar.  (Paknikar, Kishore, Madhukar, India).    PCT Int. Appl.  (2005),     29 pp.  CODEN: PIXXD2  WO  2005120173  A2  20051222  Designated States W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.  Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IS, IT, LU, MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG.  Patent  written in English.    Application: WO  2005-IN155  20050512.  Priority: IN  2004-MU548  20040512; WO  2005-IN155  20050512.  CAN 144:74815    AN 2005:1331289    CAPLUS   (Copyright (C) 2011 ACS on SciFinder (R))  

An antimicrobial formulation is disclosed contg. biol. stabilized silver nano particles stabilized by a 'green' biol. route with an av. size 1-100 nm in a carrier in which the concn. is 1 to 6 ppm.  The MIC of the stabilized silver nanoparticles for gram pos. and gram neg. bactera was 1.56-3.12 ppm.  A cream contg. 5 mg/100 g stabilized silver nanoparticles was prepd.

Origin

Europe, including Britain. The Himalayas from Kashmir to Bhutan, Assam, Western Ghats and Palni hills in South India.

Action:

Plant—astringent, alterative, vulnerary. Used in leucorrhoea, menorrhagia, bleeding piles; also in diarrhoea and dysentery. The herb is also employed as an ingredient of an ointment used for septic ulcers.

1) ALFARO, Txumari, Plantas y remedios naturales de los caminos de santiago. Barcelona: B.S.A. 2008, p. 210.

2)  HOLLINGSWORTH, Peter M., et al. A DNA barcode for land plants. Proceedings of the National Academy of Sciences of the United States of America. 2009, vol.106, nº31, p.12794-12797.
 
3) TURAN, Kadir; NAGATA, Kyosuke; KURU, Avni. Antivirial effect of Sanicula europaea L. leaves extract on influenza virus-infected cells.  Biochemical and Biophysical Research Communications. 1996, vol.225, nº1, p.22-26.

4) Khare, C.P./ Indian Medicinal Plants. -- Nueva Dheli: Springer, 2007 . - p 580.