{"tema_id":"1831","string":"Ocimum selloi Benth.","created":"2007-11-05 17:11:34","code":null,"notes":[{"@type":"Nota de alcance","@lang":"es","@value":"PARTE UTILIZADA= Used part: Inflorescencia, hojas. \n\nACCION FARMACOLOGICA= Pharmacological action: Carminativo, diafor\u00e9tico. \n\nCOMPOSICI\u00d3N QU\u00cdMICA= Chemical composition: Ocimum selloii Benth (Lamiaceae) grows in the south and southwest of Brazil and produces essential oil. This plant is used in the folk medicine and presents medicinal properties as confirmed in pre-clinical tests. The aim of this work was to evaluate the influence of two levels of solar radiation on the production and composition of essential oil of O. selloi. Plants obtained from seeds of a specimen collected in Nova Friburgo (RJ), and cultivated in Vi\u00e7osa, were grown under full solar radiation and 50 % shady. The oil was extracted by hydrodistillation and analysed by cromatography in its gas fase and mass espectrometry. The oil content and the percentage of estragole and anethole, the major compounds present in the oil, did not vary with the solar radiation intensity. During the oil extraction a partial conversion of estragole in anetole was observed. \n\nZONA GEOGRAFICA= Geografical zone: Brasil, Uruguay y NE de Argentina.\u00a0"},{"@type":"Nota de alcance","@lang":"es","@value":"DIVERSIDAD GEN\u00c9TICA Y MEJORAMIENTO DE PLANTAS MEDICINALES= Medicinal plants and improvement of medicinal herbs: \nChem. compn. anal. of the essential oil from the leaves and flowers of 2 accessions of O. selloi Benth, cultivated at the Federal University of Vicosa was carried out.\u00a0 For accession A, the major component was identified as estragole and represented 94.95 and 92.54% of the oil from the leaves and flowers resp.\u00a0 For accession B, the oil from the leaves and flowers was constituted by 65.49 and 66.18% of methyleugenol, resp.\u00a0 For both accessions, several minor constituents were also identified.\u00a0 The phenotypic and chem. differences obsd. between these 2 accessions suggest the existence of 2 chem. distinct varieties for O. selloi Benth.\u00a0\u00a0 "},{"@type":"Nota de alcance","@lang":"es","@value":"\u00daLTIMOS AVANCES EN LA QU\u00cdMICA Y ACTIVIDADES BACTERIOL\u00d3GICAS EN LAS PLANTAS MEDICINALES= Medicinal plants, last advances on chemistry and bacteria activities on the medicinal herbs\n1) Ocimum selloi essential oil (2, 20, and 200 mg\/kg; p.o.) reduced, in a dose-dependent way, the abdominal contraction induced by acetic acid (0.6%; i.p.) and the diarrhea episodes induced by castor oil in mice.\u00a0 At the higher dose (200 mg\/kg; p.o.), the essential oil significantly reduced intestinal transit (P < 0.05) in the charcoal meal test.\u00a0 The main component detected in O. selloi essential oil was Me chavicol (98%; GC and GC\/MS).These effects seems to support the use of O. selloi against diarrhea, intestinal spasm and visceral pain\n\n2) Ocimum spp. (Lamiaceae) and their essential oils have been traditionally used to kill or repel insects, and also to flavor foods and oral products, in fragrances, in folk medicine and as condiments.\u00a0 In Brazil, Ocimum selloi has been used to treat stomachaches and as an anti-inflammatory remedy.\u00a0 This study was performed to provide data on the chem. compn., acute toxicity, mutagenicity, skin irritant potential and mosquito repellency of Ocimum selloi oil.\u00a0 GC\/MS anal. of Ocimum selloi oil revealed that its major constituents were methyl-chavicol or estragole (55.3%), trans-anethole (34.2%), cis-anethole (3.9%) and caryophyllene (2.1%).\u00a0 Ocimum selloi oil given by gavage to adult Swiss Webster mice produced no adverse effects at doses as high as 1250 mg\/kg body wt.\u00a0 Deaths and symptoms (e.g. hypoactivity, ataxia and lethargy) were obsd. at doses \u00b31500 mg\/kg body wt., being females apparently more susceptible than males.\u00a0 Genotoxicity of Ocimum selloi oil was evaluated in the Salmonella\/microsome assay without and with S9 mixt.\u00a0 The oil, tested up to the toxicity limit (500-700 mg\/plate), was not mutagenic to tester strains TA97a, TA98 and TA100.\u00a0 None of 30 volunteers of either sex exposed to undiluted Ocimum selloi oil (4-h patch test) showed a pos. skin irritant reaction.\u00a0 A field test (six volunteers, each individual his\/her own control) was carried out to evaluate mosquito (Anopheles braziliensis) repellency of Ocimum selloi oil dild. in ethanol (10% vol.\/vol.).\u00a0 The median no. of mosquito bites on volunteers' skin-recorded for 30 min after application of Ocimum selloi oil (2, range 0-3) was much lower than that noted after application of the solvent alone (19.5, 3-25) (Wilcoxon test, P"},{"@type":"Nota bibliogr\u00e1fica","@lang":"es","@value":"1) TOURSARKISSIAN, Mart\u00edn. Plantas medicinales de Argentina : sus nombres bot\u00e1nicos, vulgares, usos y distribuci\u00f3n geogr\u00e1fica. Buenos Aires : Hemisferio Sur, 1980, pp.63-64.\n\n2) GONCALVES, L.A., et al. Production and Composition of Essential Oil of \"Alfavaquinha\" (Ocimum selloi Benth.) in Response to Two Levels of Solar Radiation | Revista Brasileira de Plantas Medicinais. 2003, vol.6, n\u00ba1, p.8-14. \n\u00a0\n3) MARTINS, Ernane R., et al. Essential oil in the taxonomy of\u00a0 Ocimum\u00a0\u00a0 selloi\u00a0 Benth.\u00a0 Journal of the Brazilian Chemical Society. 1997, vol.8, n\u00ba1, p.29-32. \n\u00a0\n4) FRANCA, Carolina S., et al. Analgesic and antidiarrheal properties of Ocimum selloi essential oil in mice. Fitoterapia. 2008, vol.79, n\u00ba7-8, p.569-573. \n\u00a0\n5) PADILHA DE PAULA, Josiane, et al. Chemical composition, toxicity and mosquito repellency of Ocimum selloi oil.\u00a0\u00a0 Journal of Ethnopharmacology.2003 , vol.88, n\u00ba2-3, p.253-260. "}]}